Compounded NAD+ nasal spray bottle

Filled by a licensed US pharmacy we chose. See which one

Longevity

NAD+ nasal spray

Compounded NAD+, 15 mL daily nasal spray

NAD+ in a spray you use once a day, with no needles. Prescribed by a Seattle provider and filled by a licensed US pharmacy we chose.

$179/month

Billed monthly.

  • Online or video visit with a Seattle provider
  • Medication from a pharmacy we chose
  • Follow-ups in your patient portal, as often as you'd like

You only pay if a provider prescribes.

Every prescription gives 50 meals a month to those in need.

What it is

How NAD+ works

NAD+, short for nicotinamide adenine dinucleotide, is a molecule every cell in your body makes and uses. The spray puts compounded NAD+ in a bottle you use in your nose.

EnergyMaking energy

Your cells use NAD+ in the chain of reactions that turns the food you eat into energy they can use.

RepairRepairing DNA

Enzymes called PARPs use up NAD+ each time they repair damaged DNA, so cells keep making more.

Prefer an injection? See NAD+ injection

Your daily routine

NAD+ nasal spray is part of your day, every day. How many sprays you use is set by your provider, and your pharmacy label shows the exact number.

Mon
Tue
Wed
Thu
Fri
Sat
Sun

Every day. The number of sprays is on your pharmacy label

  1. Clear your nose

    Gently blow your nose before you spray.

  2. Shake and prime

    Take off the cap and shake the bottle. The first time you use it each day, you may need to spray into the air until a fine mist comes out.

  3. Get in position

    Tilt your head forward slightly and breathe out slowly. Close the other nostril with a finger.

  4. Spray as you breathe in

    Point the nozzle toward the back of your head and squeeze the pump as you start to breathe in slowly through your nose. Repeat for the other nostril, and for each spray on your label.

  5. Let it settle

    Try not to sneeze or blow your nose right after you spray.

Steps from American Family Physician's patient guide to using nasal sprays. Your provider's directions and your pharmacy label come first.

The research

What the studies found

NAD+ nasal spray hasn't been tested in large randomized clinical trials for wellness or anti-aging use. The studies below are an animal study of NAD+ given through the nose and a study of NAD+ levels in people.

Through the nose, in rats

Intranasal NAD+ and brain NAD+

NAD+ given through the nose raised NAD+ levels in the brains of rats.

Researchers gave rats 10 mg/kg of NAD+ through the nose in a model of brain injury. The study was in animals, and it did not test wellness use in people.

Ying et al., Frontiers in Bioscience, 2007.
NAD+ and age

NAD+ in skin from 49 people

Older donors had less NAD+ in their skin.

Researchers measured NAD+ in skin samples from newborns to people aged 77 and found lower levels with age in both men and women. The study measured levels and did not test a treatment.

Massudi et al., PLoS One, 2012.

Neither study tested compounded NAD+ nasal spray in people. Compounded medications are not FDA approved, and the FDA does not review them for safety, effectiveness or quality. Individual results vary.

First weeks

What to expect in your first weeks

The first weeks are about building the habit. Here's what happens, in order.

  1. Before day 1Your spray arrives

    Your pharmacy ships your bottle to your door. Store it the way your pharmacy label says, keep it out of sunlight and check the beyond-use date on the label.

  2. Day 1Your first sprays

    Prime the pump, then use the number of sprays on your label. Pick a time of day you can stick with, like when you brush your teeth.

  3. First weeksWhat's common

    Stinging, irritation or a nosebleed can happen with nasal sprays. Aiming toward the back of your head, not the middle of your nose, helps cut down on irritation.

    If your nose hurts, stings or bleeds, or anything else doesn't settle, message your provider in your patient portal.

  4. After you startChecking in

    Questions about your sprays, your routine or how it is going go to your provider in your patient portal. You can also book a video visit at no extra cost.

Using other nasal sprays?

Tell your provider about decongestants, allergy sprays or saline sprays you use, and about colds or sinus problems, so they can advise on timing.

Something look off?

If your bottle or delivery looks off, email hello@jointhebrightside.com before you use it.

Get medical help right away

For chest pain or a racing heartbeat, trouble breathing, or swelling of your face, lips or throat.

Nasal spray tips from American Family Physician. There is no FDA prescribing information for NAD+ nasal spray. Your provider's directions and your pharmacy label come first.

How it works

Choose how you meet your provider

StartPick a treatmentAnswer a few health questions online. No office visit and no insurance needed.
OnlineProvider reviewA Seattle provider reviews your answers and messages you if they have questions.
VideoMeet your providerBook a video visit if you'd rather talk it through face to face.
PrescriptionPay only if prescribedYour visit, online or on video, is included in the treatment price. If a provider doesn't prescribe, you're not charged.
DeliveryFilled and shippedThe pharmacy we chose for your treatment fills it and ships it to your door.
After deliveryOngoing careFollow up with your provider in your BrightSide patient portal as often as you'd like.
Who is behind it

Who fills it and who prescribes it

Your pharmacy

Our pharmacies

We grade the pharmacies we work with in five categories. More than eighty compounding pharmacies have been through our grading so far.

  • What we look atWho they are, what they can make, their record, where the ingredients come from and whether it works in practice.
  • Named on our siteOur pharmacy network page names each pharmacy that fills orders today and why we chose it.
  • Licensed US pharmaciesEvery prescription is filled by a licensed US pharmacy we chose.
See our pharmacies
Dr. Shannon AroraDr. Sean Arora
Your providers

Arora Health, Seattle

A physician-led medical group. A licensed provider reviews every visit and every dose change.

  • Dr. Shannon Arora, MDChief medical officer, Arora Health
  • Dr. Sean AroraFounder, Arora Health
Meet our medical team
Support

Support once you start

Your patient portalFollow up with your provider in your BrightSide patient portal as often as you'd like.
Video visitsBook a video visit with a provider at no extra cost.
A person, by emailEmail hello@jointhebrightside.com and a person answers.
Dr. Shannon AroraDr. Sean Arora

The same providers, after you start

A licensed provider from Arora Health in Seattle reviews every visit and every dose change. Questions about your dose, side effects or what comes next go to them in your patient portal.

Questions

NAD+ nasal spray questions

Is NAD+ nasal spray FDA approved?

No. NAD+ nasal spray is a compounded medication, made by a state-licensed pharmacy for one patient from a prescription. There is no FDA-approved NAD+ nasal spray, and the FDA does not review compounded drugs for safety, effectiveness or quality.

How many sprays will I use?

Your provider sets the number of sprays with you, and your pharmacy label shows it. If it changes, your new label shows it.

How is the spray different from the injection?

Both are compounded NAD+. The spray is a daily routine with no needles, and the injection goes under the skin. No study has compared the two. Your provider can help you choose. See NAD+ injection

Can I use it with a cold or allergies?

Tell your provider about congestion, sinus problems or other nasal sprays you use, and they can advise on timing.

Can I use it with my other supplements?

Tell your provider about every medication and supplement you take, so they can review the full picture before prescribing.

Which pharmacy fills my prescription?

A licensed US pharmacy we chose. Our pharmacy network page names each pharmacy that fills orders today and its licenses.

How is it shipped?

Your pharmacy packs your bottle and ships it to your door. Store it the way the label says. If anything about your delivery looks off, email hello@jointhebrightside.com before you use it.

Do I need insurance?

No. Insurance isn't needed, and your visit, online or on video, is included in the treatment price.

What if the provider says no?

You're not charged. Your card is only charged if a licensed provider prescribes your treatment.

Compounded NAD+ nasal spray, prescribed in Seattle

$179/month

Billed monthly.

You only pay if a provider prescribes.

Important safety information

NAD+ nasal spray is a compounded medication. Compounded medications are not FDA approved, and the FDA does not review them for safety, effectiveness or quality. There is no FDA-approved NAD+ nasal spray, and it has not been tested in large randomized clinical trials.

Nasal sprays can cause stinging, irritation and nosebleeds. Tell your provider about every medication and supplement you take, including other nasal sprays and decongestants, any heart, lung, sinus or nasal condition, frequent nosebleeds or nasal surgery, and if you are pregnant, breastfeeding or planning to become pregnant.

Get medical help right away for chest pain, a racing heartbeat, trouble breathing, or swelling of your face, lips or throat.